CDER Division of Applied Regulatory Science’s (DARS) Purchase of Cryopreservation System

The objective of this project is the purchase of an additional high-performance cryopreservation freezer to complement our older existing MVE freezers thereby enhancing overall cryogenic storage capacity while reducing downtime caused by maintenance issues with older freezers. The new cryogenic freezer must be compatibility with our older existing cryogenic MVE Biological Solutions (MVE) systems in terms of storage conditions in order to minimize study to study variations. The high-performance cryopreservation characteristics of MVE systems will provide multiple benefits over conventional systems including but not limited to holding temperatures stable from top to bottom of vacuum vessel sealing cork top for near 100% enclosure, keeping the samples and liquid nitrogen separate and ease of access so maintenance can be performed without moving samples. The new system’s benefits will ensure that samples collected from projects in DARS including drug metabolism, invitro drug testing, pharmacokinetic, pharmacodynamic and toxicology studies are stored safely and that storage conditions are identical between the new and existing cryogenic freezers.