AN11--NOTICE OF INTENT TO SOLE SOURCE - SINGLE-CELL RNA SEQUENCING AND COMPUTATIONAL ANALYSIS OF MEMORY CD8+T LYMPHOCYTES FOR THE VA SAN DIEGO HEALTHCARE SYSTEM

NOTICE OF INTENT TO SOLE SOURCE The Department of Veterans Affairs, Network Contracting Office (NCO) 22, located at 4811 Airport Plaza Drive, Long Beach, CA 90815 is issuing this Notice of Intent (NOI) to inform industry contractors of the Government s intent to execute a Sole Source Award under FAR Part 13 Simplified Acquisition Procedures (SAP), specifically FAR Subpart 13.5 Simplified Procedures for Certain Commercial Items. The intended Contractor is UCSD INSTITUTE FOR GENOMIC MEDICINE located at 9500 Gilman Drive, La Jolla, CA 92093. The place of performance is at the VA San Diego Healthcare System located at 3350 La Jolla Village Dr, San Diego, CA 92161-0002. This requirement shall be used to provide single-cell RNA sequencing and computational analysis of memory CD8+T Lymphocytes. The contractor shall provide single-cell captures, library preparation, single-cell RNA-sequencing and computational analytical approaches to understand specification of the memory CD8+ T lymphocyte fates. Specifically, the 10x Genomics System is a scalable single-cell RNA-seq platform that allows analysis of gene expression profiles from tens of thousands of individual cells. The 8-sample chip is loaded with the Gel Beads, 1ng of high molecular weight DNA, and an oil-surfactant solution. Reagents and cells are combined at a microfluidic junction where Gel Bead-containing emulsions (GEMs) are generated. GEMs are created in such a way that <5 fg of DNA are partitioned with a unique molecular barcode. The workflow creates up to ~1,000,000 GEMs per channel in a 20-minute run. This procurement is being conducted using commercial item procedures pursuant to FAR Part 12 and FAR Part 13, specifically FAR Subpart13.106-1(b)(1)(i) allowing the Contracting Officer (CO) to solicit from one source. This will be a Firm Fixed Price (FFP) award and an anticipated award date is set for 08/20/2021. The proposed period of performance shall be from September 1, 2021 through November 30, 2021 (Base year). Total estimated value for the Base Year is $76,450.00. The North American Industry Classification System (NAICS) for this requirement is, 541715 Research and Development in Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology). Product of Service Code for this requirement is, AN11 Health R&D Services; Healthcare Services; Basic Research. The Small Business Administration (SBA) size standard for this sector is 1,000 employees. This notice of intent is neither a formal solicitation nor a request for competitive proposals. No solicitation document is available and telephone requests will not be honored. No award will be made on the basis of unsolicited quotations or offers received in response to this notice. Any response to this notice must show clear, compelling and convincing evidence that competition will be advantageous to the Government. The intent of this synopsis is for informational purposes only. A determination by the Government not to compete this action based on this notice is solely within the discretion of the Government. All inquiries and concerns must be addressed in writing via e-mail to Haig Altunian at [email protected] with the following information referenced in the subject line, Notice of Intent to Sole Source 36C26221Q1051 SINGLE CELL RNA SEQUENCING AND CUMPUTATIONAL ANALYSIS. A determination by the Government not to compete this proposed procurement based on the responses to this notice is solely within the discretion of the Government. Information received will be considered solely for the purpose of determining whether to conduct a competitive procurement. All interested parties who are responsible, certified, and capable may identify their interest and may submit an offer or quotation which shall be considered by the agency no later than 3:00 PM Pacific Standard Time (PST) on July 28, 2021 to Haig Altunian at [email protected]. The interested parties bear full responsibility to ensure complete transmission and timely receipt.