NOTICE OF INTENT TO SOLE SOURCE The Department of Veterans Affairs, Network Contracting Office (NCO) 22, located at 4811 Airport Plaza Drive, Long Beach, CA 90815 is issuing this Notice of Intent (NOI) to inform industry contractors of the Government s intent to execute a Sole Source Award under FAR Part 13 Simplified Acquisition Procedures (SAP), specifically FAR Subpart 13.5 Simplified Procedures for Certain Commercial Items. The intended Contractor is Life Technologies Corporation located at 5791 Van Allen Way, Carlsbad, CA 92008. This requirement shall be used to provide gene-edited isogenic HUES9 stem cells that carry PERK alleles linked to Alzheimer s Disease at the VA San Diego Healthcare System (VASDHS). The contract period shall be for one (1) base year. The contractor shall use CRISPR-Cas9 gene editing to introduce 3 SNPs that lead to 3 amino acid changes in the PERK protein. As a control, the contractor shall also create a mutation that leads to no PERK protein generation. The resulting isogenic cells shall enable direct examination of the role of PERK proteins in stem cells, and in neurons and glia differentiated from these stem cells carrying mutant PERK alleles. The contractor shall deliver multiple clones of the PERK gene-edited products. This procurement is being conducted using commercial item procedures pursuant to FAR Part 12 and FAR Part 13, specifically FAR Subpart13.106-1(b)(1)(i) allowing the Contracting Officer (CO) to solicit from one source. This will be a Firm Fixed Price (FFP) award and an anticipated award date is set for 08/01/2019. The place of performance is at the VA San Diego Healthcare System (VASDHS) located at 3350 La Jolla Village Dr., San Diego, CA 92161-0002. The North American Industry Classification System (NAICS) for this requirement is, 325414 Biological Product (except Diagnostic) Manufacturing. Product of Service Code for this requirement is, AN11 R&D Medical: Biomedical (Basic Research). The Small Business Administration (SBA) size standard for this sector is 1,250 employees. This notice of intent is neither a formal solicitation nor a request for competitive proposals. No solicitation document is available and telephone requests will not be honored. No award will be made on the basis of unsolicited quotations or offers received in response to this notice. Any response to this notice must show clear, compelling and convincing evidence that competition will be advantageous to the Government. The intent of this synopsis is for informational purposes only. Information received will normally be considered solely for the purpose of determining whether to conduct a competitive procurement. A determination by the Government not to compete this action based on this notice is solely within the discretion of the Government. All inquiries and concerns must be addressed in writing via e-mail to Haig Altunian at
[email protected] with the following information referenced in the subject line, Notice of Intent to Sole Source 36C26219Q0932 GENE EDITING SERVICES. A determination by the Government not to compete this proposed procurement based on the responses to this notice is solely within the discretion of the Government. Information received will be considered solely for the purpose of determining whether to conduct a competitive procurement. All interested parties who are responsible, certified, and capable may identify their interest and may submit an offer or quotation which shall be considered by the agency no later than 12:00 PM Pacific Standard Time (PST) on July 29, 2019 to Haig Altunian at
[email protected]. The interested parties bear full responsibility to ensure complete transmission and timely receipt.