Single Source Cooperative Agreement to Support HPAI H5N1 Research at Cornell University (U18) - Clinical Trails Not Allowed

The Food and Drug Administration's (FDA) Center for Food and Safety and Applied Nutrition (CFSAN) is announcing its intention to receive and consider a single source application for the award of a cooperative agreement in fiscal year 2024 to Cornell University to support the Center for Veterinary Medicine and the College of Agricultural and Life Sciences. The purpose of this support is to: 1. Carry out multidisciplinary applied research projects on raw milk cheese aging to examine factors that affect Highly Pathogenic H5N1 Avian Influenza (HPAI H5N1) virus inactivation, to include pH and water activity. 2. Carry out multidisciplinary applied research projects on commonly used acidification methods for treatment of waste milk to be fed to calves, or for disposal, to understand effects on HPAI H5N1. 3. Carry out multidisciplinary applied research projects to characterize the thermal inactivation kinetics of HPAI H5N1 in a wide variety of dairy products. 4. Provide additional capabilities and capacity for HPAI H5N1 testing as needed to help meet the needs of FDA's research agenda. 5. Engage with academic and industry stakeholders to help ensure work is complementary of other ongoing research in these research spaces and to facilitate the use of the information produced by the research program.