Continuing to enhance Global Health Security by sustaining efforts and strategies to protect and improve public health globally.

This Notice of Fuding Opportunity (NOFO) seeks to build upon activities funded by CDC to support Global Health Security (GHS) through implementation of programs and activities that focus on protecting and improving health globally through partnerships with Ministries of Health and other governmental institutions. This NOFO will build on lessons learned from the global COVID outbreak and other significant public health events.After ten years of implementing and strengthening global health security systems, the U.S. Government (USG) will continue to advance prevent, detect, and respond strategies to mitigate threats. This NOFO's main outcomes are to:- Improve prevention of avoidable epidemics including naturally occurring outbreaks and intentional or accidental releases of dangerous pathogens- Improve ability to rapidly detect threats early, including detecting characterizing, and reporting emerging biological threats- Responding rapidly and effectively to public health threats of international concern